Identification and Functional Analysis of a Novel Protein Through Homologous Comparison with MECP2 in Homo sapiens

A Bioinformatics Analysis of Gene, Structure, and Function

By: Abdulrazag Alhaddad and Marlon Valladares

Cell and Molecular Biology Laboratory, Spring 2026

Dr. Paramjeet S. Bagga

Published: 05/05/2026

Objectives

Identify the closest homolog of a novel purified protein using sequence alignment tools
Analyze the genomic organization of the homologous gene, including exons, introns, and regulatory regions
Compare mRNA transcript variants to investigate alternative splicing
Predict the structure and functional domains of the homologous protein
Propose future experiments to validate structural and functional predictions